BioResearch-AI

An AI-powered research assistant for biomedical literature discovery, evidence synthesis and scientific reasoning.

Agentic AI LLMs RAG Biomedical AI Python

Overview

BioResearch-AI explores how agentic AI systems can assist scientists by combining large language models, retrieval systems, literature analysis and structured reasoning workflows.

The objective is to build an extensible platform capable of supporting biomedical researchers throughout the scientific discovery process.

The Problem

Biomedical research produces an enormous amount of information: scientific publications, datasets, experimental results and clinical evidence.

Researchers often spend significant time searching literature, comparing findings and synthesizing evidence before reaching scientific conclusions.

BioResearch-AI investigates how AI systems can reduce this information bottleneck while keeping scientists in control of the final decisions.

Demo

BioResearch AI demonstration

Scientific Workflow

Research Question
Literature Search
Paper Retrieval
AI Summaries
Evidence Synthesis
Executive Report
Citation Validation

The system transforms a natural language research question into a structured evidence-based report while maintaining traceability between conclusions and supporting publications.

Key Capabilities

Literature Discovery

Search biomedical publications using natural language queries.

Evidence Synthesis

Combine findings from multiple studies into coherent summaries.

Citation Awareness

Keep generated conclusions connected to supporting scientific evidence.

Agentic Workflows

Coordinate multiple AI capabilities into scientific reasoning pipelines.

Application Example

Example research question:

Can GLP-1 receptor agonists slow the progression of Alzheimer's disease?

BioResearch-AI can:

  • Search PubMed
  • Retrieve relevant publications
  • Generate paper summaries
  • Compare evidence across studies
  • Produce a citation-aware executive report

Software Architecture

BioResearch AI architecture

The project follows Clean Architecture and Domain-Driven Design principles.

Presentation
Application
Domain
Infrastructure

This separation allows AI providers, databases, APIs and user interfaces to evolve independently while keeping the core logic testable.

Technology Stack

Python FastAPI React TypeScript TailwindCSS LangGraph OpenAI API PubMed API SQLAlchemy

Engineering Principles

Modular

Components are designed to be replaceable and extensible.

Replaceable

Different AI providers and data sources can be integrated through adapters.

Testable

Core scientific workflows remain isolated from external dependencies.

Future Directions

  • Multi-agent scientific collaboration
  • Long-term research memory
  • Knowledge graph integration
  • MCP-based scientific tools
  • Automated experimental planning

Repository

Source code, documentation and implementation details:

GitHub Repository